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Dr. Yuichi Mori and Dr. Hiroshi Yoshioka (Polymer Scientists, Waseda University, Tokyo, Japan) came with the concept of chemically constituted scaffolds to be suitable as ideal ones for invitro cell culture
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In middle 90s Dr. Kazutoshi Haraguchi, a nano material expert from Kawamura institute, Chiba, Japan started working on transparent nanosheets and membranes to aid invitro expansion of highly sensitive cells and tissues of the body.
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In 1998, Nichi-in consortium was formed headed by Mr. Yoshio Morozumi comprising of the above scientists and Dr. Samuel Abraham from Yamanashi University , Japan
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In 2002, Nichi-In Biosciences was started as a private limited company and research on corneal limbal stem cells was started with Sankara Nethrlaya, Chennai
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A MoU was signed between Nichi-In and SN in Feb 2004 in the presence of Yuichi Mori with Dr. H.N. Madhavan as the principal investigator of the study
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In march 2006, the first initiatives for corneal endothelial stem cells was taken up with Joseph eye hospital, trichy with Dr. Nelson Jesudasan as the principal investigator and Dr. John Sudhakar as the co-investigator
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Subsequently MoU’s were signed with Light Eye Hospital, Dharmapuri (Dr. P. parikumar), Aditya Jyot Eye hospital , Mumbai (Dr. Natarajan), Dharsan Eye Hospital, Chennai (Dr. Srinivas K Rao) and also collaborative arrangement with Dr. Aditya Insaan
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Dr. Shiro Amano of University of Tokyo helped us with the invitro expansion of corneal endothelial precursors
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In 2009 a collaborative arrangement was signed with the M/S. Visiontech Sdn Bhd, Kuala Lumpur, Malaysia headed by Mr. S.P. Danabalan